Nicotine potentiates the carcinogenic effect of other substances from smoke snuff and the effects of carcinogens in the environment.

Nicotine acts on the mechanism of apoptosis, or cell death, preventing the cells to commit suicide. When it comes to cancer cells does the same thing which causes or encourages the formation of lung cancer.

In addition to snuff, there are other substances mentioned above which are listed now:

Asbestos: people who work with asbestos are seven times more likely to develop cancer than those who do not maintain contact with it. These people have a type of cancer called mesothelioma, which occurs in the pleura. In recent years, governments have banned the use of this material for commercial and industrial products. When combined with asbestos exposure to smoking, it increases their chances of getting cancer from 50 to 90 times.

Cancer-causing agents in the workplace: an occupational risk group are the miners. They work with materials that, when inhaled, can damage your lungs. Such substances are radioactive minerals such as uranium, and workers exposed to chemicals such as arsenic, vinyl chloride, nickel chromates, coal based products, mustard gas and chloromethyl ethers. People working in these conditions should be careful to avoid exposure to these agents.

Other factors would be those that have produced some damage to the lung and predispose them to cancer, as having suffered tuberculosis, silicosis or berilosis (diseases, the latter two, caused by inhalation of certain minerals).

Another reason that favors the growth of cancer cells would be the excess or deficit of vitamin A.

Noting the risk factors seem easy to prevent this disease. The no smoking or quit is the most effective measure in preventing cancer.