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Cancer cells develop from normal cells in a complex process called transformation. The first step is the initiation process in which a change in the cell’s genetic material prepares to become cancerous. This change is caused by an agent called a carcinogen (may be a chemical, a virus, radiation, or sunlight). However, not all cells are equally susceptible to carcinogens. A genetic defect in the cell or other agent, known as a promoter, including chronic physical irritation may increase the ability of cells to become cancerous.
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