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A multitude of factors, genetic and environmental, increase the risk of developing cancer.
Family history is an important factor. Some families have a much higher risk of developing certain cancers than others. For example, the risk of developing breast cancer in women increases from 1.5 to 3 times if the mother or sister had this type of cancer. Some breast cancers are linked to a specific gene mutation more common in some ethnic groups and in some families.
Women with this genetic mutation have between 80 and 90 percent chance of developing breast cancer and 40 to 50 percent of ovarian cancer. Researchers have found that one percent of Ashkenazi Jewish women have this genetic mutation. Many other cancers, including some types of skin cancer and colon cancer, also tend to affect entire families. People with chromosomal abnormalities have an increased risk of cancer.
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