Archive for the ‘Cancer’ Category

An increased risk of pancreatic cancer with consumption of meat

The pancreatic cancer is one of the cancers most lethal amounting to 5% survival rate at 5 years. Scientists have focused their analysis of seven studies. They were able to show an increase of 50 grams in the consumption of meats per day increases the risk of cancer of the pancreas. This risk would amount to 19% for men and women.

Explanations

These results are explained by the fact that the processes of conservation of meat involve hazardous constituents for health . Indeed, conservation is done with nitrites (salts of nitrous acid with its presence in human blood prevents hemoglobin oxygen set correctly). Moreover, these additives will form nitrosamines in meat found to be highly carcinogenic. They are likely to arrive until the pancreas and cause cancer.

To prevent the risk of pancreatic cancer, it is recommended that:

• have a reasonable consumption of meats and monitored at 500 grams per week (maximum amount not to cross)
• Avoid smoking because tobacco also contains nitrosamines.

The intrinsic relationship between cancer and obesity

Both in France and the United States, we see a decrease in the rate of deaths from cancer . The heralds of the good news are the authors of the annual report of the American Society of Oncology. However, they can not hide their concern over the emergence of cancers that are rare and little known and which could be caused by obesity.
BMI and cancer

In the U.S., since 1990, the rate of deaths from cancer fell by 23% in men and 15% in women. During the last two decades, approximately one million deaths from cancer were averted. It turns out that this is due to the many campaigns of screening and prevention have been conducted over the past three decades.

However, it was observed that there was a considerable increase in the number of cases of unusual cancers such as cancers of the liver, pancreas, thyroid, esophagus, kidney, skin and throat . According to the American Cancer Society, “the reasons for this increase are not all known” but the professional health argue that many of these diseases is linked to obesity.

A correlation has been established in 2008 by British scientists, between BMI (body mass index) and risk of cancer predisposition. For the year 2012, the American Society of Oncology anticipate 1.6 million cancer cases diagnosed in the United States. The number of deaths would amount they estimate at 577,000. It should be noted that in France, 365 000 cancer cases were detected in 2011 killing 145,000 patients .

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Mesothelioma: notifiable disease

Mesothelioma has been declared recently as disease notifiable. This term means that the doctor who diagnosed the disease in the patient must inform the health authorities. The objective of this decree is to better understand this rare type of cancer by identifying the causes.
A rare cancer

Mesothelioma is a cancer often located in the peritoneum. The National Cancer Institute (INCA) claims to have identified between 800 and 1200 cases of mesothelioma each year. These figures represent only 0.3% of all cancers .

Exposure to asbestos at work is the main cause of this cancer. It is good to know that asbestos is a highly toxic mineral used in building construction.
The objectives

The National Mesothelioma Surveillance uses this order to try to identify risk factors for mesothelioma other than asbestos exposure in order to strengthen their program of surveillance and prevention. Physicians must complete a form available at the INVS to report a case of mesothelioma.

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PIP: Breast implants for cancer centers

The company PIP (Poly Implant Prosthesis) breast implants would have provided a multitude of cancer centers in 2010.
Prostheses dangerous

Remember, PIP is at the heart of the controversy in France for products manufactured using industrial silicone, a substance does not comply with regulations. Following the death of lymphoma in a woman with implants, the government has even used the IPP clients and encourages them to be removed implants as a precautionary measure.

Several centers fighting against cancer , such as the Institut Curie and Institut Gustave Roussy, have used the products as part of breast reconstruction in women with the disease . Experts believe that the affordability of implants have contributed to its popularity. At least sixteen of eighteen clinics have used the defective implants.

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Formation of cancer cervix

The organization INCA (the Institute of Cancer ) has established a training system to help physicians and midwives to become more familiar with the symptoms of cancer of the cervix. These in-depth learning modules also optimize early detection of disease .

Improved knowledge

This device is included in the Cancer Plan 2009-2013, which aims to reduce the number of cancers in the world. Midwives and doctors will be able to improve the quality of care. The training promotes and encourages a gynecological consultations contraception .

Measures such as screening Pap test, examination and simple HPV vaccine are also discussed in the program. As a result, professionals expect lower the incidence of cervical cancer through medical practices reinforced. Researchers at the National College of obstetricians have contributed to the development of modules.

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Metastasis or skeletal

Bone metastasis occur especially in people with cancer of the breast, lung or prostate. Bone metastases are not always identifiable. There are now ways to help prevent this disease .
Implications

Metastases are characterized by inflammatory pain occurring at night and intensified when the body is making efforts. A long-term pain is more acute, up to the fracture of bone or hypercalcemia. These are caused by excess calcium.
Moreover, metastases can cause nerve root compression or spinal cord.
Metastases can affect the autonomy of patients.
Treatments

Radiation is used to ease pain effectively. Patients can be treated both as surgery or the administration of bisphosphonates. These are effective in slowing bone complications.

Denosumab, a new drug will soon be on the market. It aims to prevent bone problems in people with tumors. In fact this drug makes the frame stronger bone. In addition, denosumab slows the onset of fracture.

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Prostate cancer: discovery of a genetic mutation

We have conducted numerous studies over several years to understand the causes of cancer and to find appropriate remedies. The cancer of the prostate is the type most common cancer in men. The fruit of 20 years of continuous efforts was published in the New England Journal of Medicine.

The researchers were able to obtain clarification of the mechanism of development of prostate cancer. The gene HOXB13 is responsible for a genetic mutation.
Important discovery

Studies have shown that a genetic mutation may increase the risk of transmission of hereditary prostate cancer. This type of cancer can be passed from father to son and the young male members of a family are spared.

William Isaacs, Professor of Urology, Faculty of Medicine says that this discovery is a major step in the search for methods of prevention against cancer. It is now possible to perform screening campaigns on individuals at risk. Such a campaign is on the agenda for 2012 and more than 240,000 people expected to attend.

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Down syndrome give new options for cancer treatment

People with Down syndrome may hold the key to the initiation of new studies and research to assist the treatment of cancer patients .

Until recently, experts on the subject did not have an accurate answer to why people with Down syndrome were not affected much by the cancer , except in a few cases.

Recently, scientists at Children’s Hospital in Boston found that the same factor that produces Down syndrome prevents tumors continue to develop, we are referring to a copy of chromosome 21.

Most people have two copies (one from each parent) of the 23 chromosomes that include genetic information of each of us. In the case of people with Down syndrome on chromosome 21 have one more, so that instead of having 2 have 3.

In studies with mice, they concluded that the mere presence of the extra chromosome significantly help to prevent them from growing tumors.

The discovery opens the door to a new treatment that may mean in the future an important aid for cancer patients .

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Women with kidney cancer have increased in the last three decades as a consequence of smoking

The increase in cases of kidney cancer has doubled the rate of 7 per 100,000 inhabitants in 1975 to 12/100.000 today.

This increase has been determined especially among women who smoke increase the chances of tumor risk by 35 percent.

The information has been offered in the 34 th National Congress of the Spanish Association of Urology (EAU) at Feria Valencia, adding further data related to the increase in victims of cancer as a result of changing lifestyles, poor diet and inactivity.

The determinants of tumors respond to a hereditary component , so that affects men and women having twice the incidence in males. However, women have increased in number as a result of smoking.

The detection of these tumors but today it is more accurate with new imaging techniques.

The annual increase is caused in turn by the best diagnoses currently offered and an increase in tumors in younger people as a result of smoking, for example.

However undeniable is that the removal of tumors early can turn in a better appreciation of life.

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Chromosome is a mechanism implicated in cancer

Cancer Institute Dana-Farber in the U.S. and a team of researchers have been able to find a new chromosomal mechanism might be involved in cancer development.

The research and its findings are published in the online edition of Nature magazine, where he also explains how the new molecular mechanism could weave the chromosomal instabilities are usually observed in cancer cells.
Importantly, cancer cells have an abnormal chromosome set consisting of extra centrosomes, which according to scientific research developers could promote abnormal separation of chromosomes, chromosome instability and proliferation of malignant cells.
David Pellman, who led the research says that the abnormal segregation of chromosomes arises because they can not join properly with its axis of division, a process name merotely , which has also been linked to chromosomal instability.

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